ea0056p592 | Obesity | ECE2018
Fernandez Fondevila Marcos
, Porteiro Coto Begona
, Buque Xabier
, Jesus Gonzalez Rellan Maria
, Fernandez Paz Uxia
, Mora Alfonso
, Beiroa Daniel
, Senra Ana
, Gallego Rosalia
, Lopez Miguel
, Sabio Guadalupe
, Dieguez Carlos
, Aspichueta Patricia
, Nogueiras Pozo Ruben
Introduction: p53 is transcription factor widely known because of its antitumoral actions. New evidences suggest that p53 also play a key role in the regulation of metabolic homeostasis and specifically in the lipid metabolism.Objective: We hypothesize that the chemical activation of p53 with low doses of doxorubicin could ameliorate the lipid metabolism in in vitro models of liver steatosis.Methods: We treated with low co...